» Researchers Release Compelling Evidence of Alzheimer’s Link to Early Lead Exposure

Researchers Release Compelling Evidence of Alzheimer’s Link to Early Lead Exposure

Bloomfield Hills, MI (Law Firm Newswire) January 15, 2014 - A new study has found that infant primates who were fed lead-rich formula later develop key signs of disease.

Scientists have known for some time that there are three primary risk factors for Alzheimer’s disease: advanced age, family history and genetic make-up. However, the results of a long-term study released in December has now provided solid evidence that early exposure to lead is also a key factor in the development of Alzheimer’s-induced dementia.

A team of researchers from the University of Rhode Island, Kingston (URI) conducted a 23-year study that found that macaque monkeys who were fed a lead-rich formula as infants later developed a protein called tau, which has a known association with the onset of Alzheimer’s disease. Indeed, the monkeys used in the trials were found to have three times as much irregular tau protein in their brains than infant monkeys who consumed a normal formula did.

Another telling finding showed that the genetic instructions that assemble the tau protein in the monkeys were altered after the infants outgrew the lead-tainted formula. That fact suggests that lead exposure during infancy epigenetically reprogrammed the primates‘ DNA.

An earlier, supporting study also determined that baby monkeys fed formula enriched with lead later developed brains marred by the presence of amyloid plaques very similar to the ones present in the brains of adults with Alzheimer’s disease.

The researchers’ new findings are significant because it has long been known that, even in small doses, consumption of lead can cause damage to body organs, intestines and the nervous system. Children, whose brains are in an early and normally rapid stage of development, are particularly susceptible to the deleterious effects of lead consumption. Researchers have calculated that one in 38 children in the United States has harmful levels of lead within their body.

Some neuroscientists are particularly piqued by the URI findings because the brain physiologies of macaque monkeys and humans are significantly similar. These similarities have prompted at least one specialist to call upon dementia researchers to take the results seriously.

“This study adds another important piece to this link between early-life lead exposure and Alzheimer’s-like pathology,” said Marc Weisskopf, a neuroscientist at the Harvard School of Public Health in Boston.

Up until the results of the URI team’s study were released, the link between lead consumption during childhood and the development of Alzheimer’s disease in old age was tenuous at best. Scientists continue to caution that more studies to confirm the correlation will have to be conducted. Still, the team’s findings, which were published in the December issue of NeuroToxicology, have left researchers hopeful.

“This is very strong evidence that early [lead] exposure can determine what happens in old age,” said Nasser Zawia, lead toxicologist of the URI research team.

The Elder Care Firm of Christopher J. Berry
2550 S Telegraph Rd.
Ste 255
Bloomfield Hills, MI 48302
Local: 248.481.4000
Toll free: 855-41-Elder (855-413-5337)

  • Michigan Veterans Benefits Bolstered
    <p>In a state that ranks in the bottom five in the U.S. for federal spending per veteran, there are hundreds of thousands of Michigan vets who qualify for military benefits, like healthcare and pensions.  Surprisingly, many don’t know they qualify, and others simply haven’t filed for the benefits due them. Aside from the traditional health-and-pension benefits, other Michigan Veterans Benefits include home loans as well as educational subsidies via the GI-bill; also, vets may qualify for disability claims and life insurance. What’s more, Michigan vets can tap the Michigan Veterans Trust Fund Agency (MVTFA) to receive vocational training at the...</p>
    <p>The post <a rel="nofollow" href="http://www.theeldercarefirm.com/michigan-veterans-benefits-bolstered/">Michigan Veterans Benefits Bolstered</a> appeared first on <a rel="nofollow" href="http://www.theeldercarefirm.com">Estate Planning Lawyers | Elder Law Attorneys | Brighton | Novi | Livonia Elder Law Attorneys</a>.</p>
  • Not All Living Trusts Are Created The Same
    <p>The digital age provides us with many opportunities to write our own wills, create trust documents, transfer assets. Just log on to LegalZoom and. Wait! When it comes to legal matters, and particularly when it concerns one's property and financial assets, it makes no sense to go the route of a do-it-yourself solution: forget those templates you found on the Internet, and the 'will' documents you can pick up at your local box store. What's needed, of course, is a thorough understanding of the <em>consequences </em>when you've chosen the wrong document, or forgotten to add pertinent details to legitimize your will, or trust, many years later.</p>
    <p>The post <a rel="nofollow" href="http://www.theeldercarefirm.com/compare-living-trusts/">Not All Living Trusts Are Created The Same</a> appeared first on <a rel="nofollow" href="http://www.theeldercarefirm.com">Estate Planning Lawyers | Elder Law Attorneys | Brighton | Novi | Livonia Elder Law Attorneys</a>.</p>
  • How to avoid nursing home costs: CCRCs may provide the progressive care needed.
    <p>In today’s uncertain economic times marked by roller-coaster markets and <a href="http://blogs.wsj.com/moneybeat/2013/04/16/the-best-indicator-of-u-s-health-is-wage-growth-or-lack-thereof/">flat-line wages</a>, leave it to a certain segment of Michigan seniors and retirees who are choosing to live in bigger homes instead of taking a more common route of downsizing during their retirement years.</p>
    <p>In fact, according to a recent report by Merrill Lynch and Age Wave, 49% of retirees in their survey chose not to downsize in “their last move.” Moreover, 30% were electing to move into a much larger home. Such choices obviously belong to a retirement sector quite “confident with their investments.”</p>
    <p>The post <a rel="nofollow" href="http://www.theeldercarefirm.com/how-to-avoid-nursing-home-costs-ccrcs-may-provide-the-progressive-care-needed/">How to avoid nursing home costs: CCRCs may provide the progressive care needed.</a> appeared first on <a rel="nofollow" href="http://www.theeldercarefirm.com">Estate Planning Lawyers | Elder Law Attorneys | Brighton | Novi | Livonia Elder Law Attorneys</a>.</p>
  • How to Pay for Assisted Living Costs in Michigan
    <p>During your retirement years, one of the biggest expenses you’re likely to have is paying for assisted living and long-term care costs. In fact, after taking some time researching the pricing structure for some of the assisted living communities in Livingston, Oakland or Wayne County, you might find yourself wondering out loud just how you’re going to be able to afford it all.</p>
    <p>The post <a rel="nofollow" href="http://www.theeldercarefirm.com/how-to-pay-for-assisted-living-costs-in-michigan/">How to Pay for Assisted Living Costs in Michigan</a> appeared first on <a rel="nofollow" href="http://www.theeldercarefirm.com">Estate Planning Lawyers | Elder Law Attorneys | Brighton | Novi | Livonia Elder Law Attorneys</a>.</p>

See other news sources publishing this article. BETA | Tags: , , , , ,



Get headlines from Law Firm Newswire sent right to your inbox.

* indicates required